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RSS FeedsAcquired Resistance Is Oncogene and Drug Agnostic (Cancer Cell)

 
 

15 october 2019 04:00:16

 
Acquired Resistance Is Oncogene and Drug Agnostic (Cancer Cell)
 




Recent approvals of TRK inhibitors have demonstrated the success of a tumor agnostic approach to oncogene-targeted therapy across cancers. Collective data from acquired resistance studies suggest that resistance mechanisms, which include both kinase domain mutations and bypass signaling via RTK-RAS-RAF-MAPK pathways, frequently recur regardless of tumor type, oncogene, and drug.


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27 viewsCategory: Cell Biology, Oncology
 
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