Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures (Cell)

A blastocyst-like structure is generated from a single stem-cell type as well as from somatic reprogrammed cells, and these artificial embryo-like structures can implant, induce decidualization, and give rise to cells of the three embryonic founding tissues: epiblast, trophectoderm, and primitive endoderm.