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RSS Feeds[ASAP] Discovery of AM-6494: A Potent and Orally Efficacious ß-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2 (Journal of Medicinal Chemistry)

 
 

19 october 2019 04:02:37

 
[ASAP] Discovery of AM-6494: A Potent and Orally Efficacious ß-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2 (Journal of Medicinal Chemistry)
 
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b01034


 
244 viewsCategory: Chemistry, Medicine
 
[ASAP] Protein Stability Effects in Aggregate-Based Enzyme Inhibition (Journal of Medicinal Chemistry)
[ASAP] Targeting the Side-Chain Convergence of Hydrophobic a-Helical Hot Spots To Design Small-Molecule Mimetics: Key Binding Features for i, i + 3, and i + 7 (Journal of Medicinal Chemistry)
 
 
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