Misregulation of Drosophila Myc Disrupts Circadian Behavior and Metabolism (Cell Reports)

The human MYC oncogene is involved in many cancers and disrupts the clock in cancer cells. Hsieh et al. show that dMyc, the fruit fly homolog of human MYC, plays a role in fly daily sleep-wake cycles, such that increased or decreased dMyc activity disrupts circadian behavior and metabolism.