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RSS FeedsStructural Elucidation of Viral Antagonism of Innate Immunity at the STAT1 Interface (Cell Reports)

 
 

13 november 2019 03:04:30

 
Structural Elucidation of Viral Antagonism of Innate Immunity at the STAT1 Interface (Cell Reports)
 


Hossain et al. explore the binding surface of the multifunctional P-protein of rabies virus for STAT1, a protein that is essential for establishing the antiviral response of infected cells. They identify a complex interface comprising several distinct sites and demonstrate that targeted modifications of these can significantly attenuate pathogenic virus.


 
175 viewsCategory: Cell Biology
 
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