Persistent Dengue Infection in an Immunosuppressed Patient Reveals the Roles of Humoral and Cellular Immune Responses in Virus Clearance (Cell Host & Microbe)

Examining a lymphopenic kidney transplant patient presented with dengue virus (DENV) infection, Ng et al. observed that the virus persisted in blood and urine despite detectable antibodies. Full resolution of DENV infection coincided with recovery of CD8+ counts, suggesting a role of cellular immunity in sterilizing dengue virus infection.