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RSS FeedsGenome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases (Immunity)

 
 

19 november 2019 19:03:17

 
Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases (Immunity)
 


Cildir et al. map the genomic and transcriptomic changes in human mast cells upon diverse stimuli, defining chromatin changes associated with activation and Ca2+ flux and revealing potential effectors of mast cell function. Disease-associated SNPs mapped onto cis-regulatory regions of mast cells suggest that mast cell function may impact a broad range of pathologies.


 
247 viewsCategory: Immunology
 
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