Spatiotemporal Organization of the E. coli Transcriptome: Translation Independence and Engagement in Regulation (Molecular Cell)

Despite reports that bacteria are capable of localizing RNAs to specific subcellular sites, the global prevalence of this phenomenon remained unknown. Kannaiah et al. show uneven distribution of the E. coli transcriptome and a significant translation-independent RNA localization. The unique population at the poles highlights them as hubs for regulation.