MyJournals Home  

RSS FeedsMaterials, Vol. 12, Pages 3861: Niobium-Treated Titanium Implants with Improved Cellular and Molecular Activities at the Tissue-Implant Interface (Materials)

 
 

22 november 2019 15:03:38

 
Materials, Vol. 12, Pages 3861: Niobium-Treated Titanium Implants with Improved Cellular and Molecular Activities at the Tissue-Implant Interface (Materials)
 


There have been several attempts to improve the cellular and molecular interactions at the tissue–implant interface. Here, the biocompatibility of titanium-based implants (e.g., Grade 2 Titanium alloy (Ti-40) and titanium–niobium alloy (Ti-Nb)) has been assessed using different cellular and molecular examinations. Cell culture experiments were performed on three substrates: Ti-40, Ti-Nb, and tissue culture polystyrene as control. Cells number and growth rate were assessed by cell counting in various days and cell morphology was monitored using microscopic observations. The evaluation of cells’ behavior on the surface of the implants paves the way for designing appropriate biomaterials for orthopedic and dental applications. It was observed that the cell growth rate on the control sample was relatively higher than that of the Ti-40 and Ti-Nb samples because of the coarse surface of the titanium-based materials. On the other hand, the final cell population was higher for titanium-based implants; this difference was attributed to the growth pattern, in which cells were not monolayered on the surface. Collagen I was not observed, while collagen III was secreted. Furthermore, interleukin (IL)-6 and vascular endothelial growth factor (VEGF) secretion were enhanced, and IL-8 secretion decreased. Moreover, various types of cells can be utilized with a series of substrates to unfold the cell behavior mechanism and cell–substrate interaction.


 
185 viewsCategory: Chemistry, Physics
 
Materials, Vol. 12, Pages 3862: Facile Preparative Access to Bioactive Silicon Oxycarbides with Tunable Porosity (Materials)
Materials, Vol. 12, Pages 3860: Study of Infrared Laser Parameters on Surface Morphology and Hydrophobic Properties (Materials)
 
 
blog comments powered by Disqus


MyJournals.org
The latest issues of all your favorite science journals on one page

Username:
Password:

Register | Retrieve

Search:

Physics


Copyright © 2008 - 2024 Indigonet Services B.V.. Contact: Tim Hulsen. Read here our privacy notice.
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Nachrichten