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RSS FeedsMIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes (Molecular Cell)

 
 

5 december 2019 20:00:04

 
MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes (Molecular Cell)
 


Freyre et al. identify mechanisms that couple mitochondria, the ER, and lipid droplets in white adipocytes. A combination of proteomics, lipidomics, and RNA-seq is used to discover the mitochondrial membrane protein MIGA2 with a function in organelle coupling, stimulation of TAG synthesis from non-lipid precursors, and activation of adipocyte differentiation.


 
241 viewsCategory: Molecular Biology, Cell Biology
 
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