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RSS FeedsThe Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance (Cell Reports)

 
 

11 december 2019 04:00:09

 
The Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance (Cell Reports)
 


Ciliary proteins such as Arl13b are crucial for canonical Shh signaling during neuronal development. Here, Ferent et al. investigate the role of Arl13b in non-canonical Shh signaling. They show that Arl13b is required for Shh-mediated axon guidance and that this role of Arl13b can be dissociated from its cilia localization.


 
197 viewsCategory: Cell Biology
 
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