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RSS FeedsEndogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells (Cell Reports)

 
 

11 december 2019 04:00:09

 
Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells (Cell Reports)
 


Yang et al. demonstrate that temporal regulation by insulin/IGF is essential for cell-type heterogeneity during human embryonic stem cell (hESC) differentiation. Inhibition of the endogenous IGF pathway promotes cardiomyocyte differentiation from mesoderm progenitors.


 
194 viewsCategory: Cell Biology
 
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