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RSS FeedsToxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria (Cell Host & Microbe)

 
 

11 december 2019 23:00:14

 
Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria (Cell Host & Microbe)
 




Mechanisms enabling the host to establish to a privileged relationship with commensal bacteria while preserving protective responses against pathogens remain largely unknown. Leech et al. demonstrate an early-life capacity to distinguish between commensal and pathogenic skin bacteria that preferentially facilitates accumulation of commensal-specific Tregs and immune tolerance.


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108 viewsCategory: Cell Biology, Immunology, Microbiology
 
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