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RSS FeedsMolecules, Vol. 24, Pages 4563: First Synthesis of (-)-Altenuene-D3 Suitable as Internal Standard for Isotope Dilution Mass Spectrometry (Molecules)

 
 

13 december 2019 02:03:32

 
Molecules, Vol. 24, Pages 4563: First Synthesis of (-)-Altenuene-D3 Suitable as Internal Standard for Isotope Dilution Mass Spectrometry (Molecules)
 


Metabolites from Alternaria fungi exhibit a variety of biological properties such as phytotoxic, cytotoxic, or antimicrobial activity. Optimization of a literature procedure culminated in an efficient total synthesis of (−)-altenuene as well as a stable isotope-labeled derivative suitable for implementation in a LC-MS/MS method for mycotoxin analysis.


 
209 viewsCategory: Biochemistry, Chemistry, Molecular Biology
 
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