The ArfGAP Drongo Promotes Actomyosin Contractility during Collective Cell Migration by Releasing Myosin Phosphatase from the Trailing Edge (Cell Reports)

Zeledon et al. identify the ArfGAP Drongo as a regulator of border cell migration in Drosophila. Drongo acts antagonistically to the ArfGEF Steppke on Arf51F. By keeping the activity of Arf51F low, Drongo prevents the recruitment of myosin phosphatase and ensures proper contractility at the back of border cell clusters.