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RSS FeedsActivation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51 (Cell Reports)

 
 

15 october 2019 18:00:28

 
Activation of Oncogenic Super-Enhancers Is Coupled with DNA Repair by RAD51 (Cell Reports)
 


By mapping physiological double-strand breaks (DSBs) of tumorigenic and non-tumorigenic cells Hazan et al. uncover a coupled transcription-repair mechanism at oncogenic super-enhancers in which RAD51 of the homologous recombination pathway plays a key role supporting the hyper-transcription of related oncogenes.


 
34 viewsCategory: Cell Biology
 
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