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RSS FeedsInput-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling (Neuron)

 
 

20 november 2019 18:01:05

 
Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling (Neuron)
 


Chokshi et al. demonstrate that visual experience-induced expression of H1a and its interaction with mGluR5 selectively depress intracortical synapses in an NMDAR-dependent manner. Such metaplasticity may benefit in vivo circuit function by allowing input-specific homeostatic control.


 
187 viewsCategory: Neurology
 
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