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RSS FeedsR-Loops Promote Antisense Transcription across the Mammalian Genome (Molecular Cell)


21 november 2019 20:00:54

R-Loops Promote Antisense Transcription across the Mammalian Genome (Molecular Cell)

Tan-Wong et al. demonstrate that R-loop structures, often formed at the promoter, terminator, and enhancer regions of human protein-coding genes, act as promoters to generate antisense lncRNA. In effect, R-loop promoter activity may account for the existence of many lncRNA that are detected across mammalian genomes.

54 viewsCategory: Molecular Biology, Cell Biology
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