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RSS FeedsFOXD3 Regulates VISTA Expression in Melanoma (Cell Reports)

 
 

14 january 2020 22:01:02

 
FOXD3 Regulates VISTA Expression in Melanoma (Cell Reports)
 


VISTA is an understudied immune checkpoint protein. Through the analysis of patient samples and studies in mouse models, Rosenbaum et al. investigate the functional consequences of VISTA expression on melanoma cells. Furthermore, they demonstrate that the BRAF-regulated transcription factor FOXD3 negatively regulates VISTA expression.


 
190 viewsCategory: Cell Biology
 
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