Biochemistry
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16 january 2020 18:00:46 |
| Exploring Targeted Degradation Strategy for Oncogenic KRASG12C (Cell Chemical Biology) |
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Tweet KRASG12C is an oncoprotein of high interest for drug development. Zeng et al. investigate targeting KRASG12C for degradation using small-molecule degraders (PROTACs) and document challenges and opportunities in this area. |
| 205 viewsCategory: Biology, Chemistry, Biochemistry |
 Taking the Brakes Off Targeted Protein Degradation (Cell Chemical Biology)From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9 (Cell Chemical Biology) 
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