MyJournals Home  

RSS FeedsAn mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis (Molecular Cell)

 
 

17 january 2020 01:03:28

 
An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis (Molecular Cell)
 


Odle and colleagues show that while autophagy is usually repressed by the nutrient-responsive mTORC1 kinase complex, this is not the case during mitosis. Instead, CCNB1-CDK1 catalyzes phosphorylation at the same repressive sites, taking over the role of repressing autophagy regulators. Thus, repression of autophagy is ensured regardless of nutrient availability.


 
231 viewsCategory: Molecular Biology, Cell Biology
 
Cancer-Derived Succinate Promotes Macrophage Polarization and Cancer Metastasis via Succinate Receptor (Molecular Cell)
The Biogenesis of SRP RNA Is Modulated by an RNA Folding Intermediate Attained during Transcription (Molecular Cell)
 
 
blog comments powered by Disqus


MyJournals.org
The latest issues of all your favorite science journals on one page

Username:
Password:

Register | Retrieve

Search:

Cell Biology


Copyright © 2008 - 2024 Indigonet Services B.V.. Contact: Tim Hulsen. Read here our privacy notice.
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Nachrichten