RNA-RNA Interactomes of ProQ and Hfq Reveal Overlapping and Competing Roles (Molecular Cell)

Melamed and Adams et al. compare the RNA-RNA interactomes of the well-characterized Hfq and the understudied ProQ RNA chaperones. They examine overlapping RNA pairs bound by both proteins, identify a new RNA sponge for the RybB small RNA, and document that ProQ can block Hfq activity.