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RSS FeedsSTRIPAK Limits Stem Cell Differentiation of a WNT Signaling Center to Control Planarian Axis Scaling (Current Biology)

 
 

20 january 2020 20:02:49

 
STRIPAK Limits Stem Cell Differentiation of a WNT Signaling Center to Control Planarian Axis Scaling (Current Biology)
 


Planarians must scale the relative size of tissues to accomplish regeneration. Schad and Petersen identify the mob4 and striatin components of the STRIPAK complex as negative regulators of tail size in planarians. STRIPAK acts by limiting stem cell differentiation of Wnt-expressing signaling-center cells that determine posterior scaling.


 
177 viewsCategory: Biology
 
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