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RSS FeedsAltered Hippocampal-Prefrontal Neural Dynamics in Mouse Models of Down Syndrome (Cell Reports)

 
 

28 january 2020 20:02:42

 
Altered Hippocampal-Prefrontal Neural Dynamics in Mouse Models of Down Syndrome (Cell Reports)
 


Chang et al. examine three partially trisomic mouse models of Down syndrome that together cover all regions of homology with human chromosome 21. They identify non-overlapping differences in spatial working memory function associated with distinct abnormalities in hippocampal and medial prefrontal electrophysiology.


 
187 viewsCategory: Cell Biology
 
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