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RSS FeedsOsmotic Gradients in Epithelial Acini Increase Mechanical Tension across E-cadherin, Drive Morphogenesis, and Maintain Homeostasis (Current Biology)

 
 

25 february 2020 14:00:23

 
Osmotic Gradients in Epithelial Acini Increase Mechanical Tension across E-cadherin, Drive Morphogenesis, and Maintain Homeostasis (Current Biology)
 


Narayanan et al. describe the role of ion secretion in the generation of osmotic pressure and changes in mechanical tension across E-cadherin in epithelial acini. Increasing the osmotic gradient increased force exerted across E-cadherin, induced cellular proliferation, and blocked EMT progression.


 
194 viewsCategory: Biology
 
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