Niche Cell Wrapping Ensures Primordial Germ Cell Quiescence and Protection from Intercellular Cannibalism (Current Biology)

Niche cells often enwrap stem cells. McIntyre and Nance examine niche-stem cell interactions in the gonad primordium of C. elegans, showing that niche wrapping maintains primordial germ cell quiescence by inhibiting Notch signaling and protects primordial germ cells from intercellular cannibalism.