There is a considerable amount of research concerning the issue of entrepreneurial intentions, which has attained mixed findings. Integrating sustainability, in the sense of considering disabled people, into the current entrepreneurial intention research makes it possible to fill an important research gap. The main objective of this paper is to clarify the contribution that education, students’ traits, and contextual factors make to an individual’s entrepreneurial intent when disabled students are incorporated into the analysis as an innovative field of study. The aim of this research is to analyze the entrepreneurial intentions of disabled people who are studying in higher education and compare them with non-disabled students while considering the main factors described in previous studies. In order to achieve this objective, we have carried out a logistic regression with a sample of Spanish students. The main findings are: Education does not influence students’ entrepreneurial intentions, which are affected by only some of the students’ traits and background conditions. Regarding the disabled students’ entrepreneurial intentions, we have found no significant differences compared with those of students who are not disabled. Initiatives such as those of the University of Castilla-La Mancha (UCLM) described in the paper should, therefore, be encouraged, keeping in mind that disabled students do not always show a lack of confidence in themselves as some studies have claimed.