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RSS FeedsImprinted Maternally Expressed microRNAs Antagonize Paternally Driven Gene Programs in Neurons (Molecular Cell)

 
 

2 april 2020 21:00:29

 
Imprinted Maternally Expressed microRNAs Antagonize Paternally Driven Gene Programs in Neurons (Molecular Cell)
 


Some miRNAs are regulated by genomic imprinting, but the evolutionary benefits and consequences of parental-biased miRNA expression are unknown. Whipple et al. show that maternally expressed miRNAs target transcriptional and developmental regulators, including paternally expressed transcripts, suggesting these miRNAs may increase matrilineal inclusive fitness by antagonizing paternally driven gene programs.


 
155 viewsCategory: Molecular Biology, Cell Biology
 
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