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RSS FeedsContext-Dependent Gene Regulation by Homeodomain Transcription Factor Complexes Revealed by Shape-Readout Deficient Proteins (Molecular Cell)

 
 

2 april 2020 21:00:29

 
Context-Dependent Gene Regulation by Homeodomain Transcription Factor Complexes Revealed by Shape-Readout Deficient Proteins (Molecular Cell)
 


High-throughput in vitro DNA binding assays reveal DNA shape readout by homeodomain transcription factors. Mutations that impair this readout are used to selectively destabilize specific homeodomain complexes both in vitro and in vivo.


 
184 viewsCategory: Molecular Biology, Cell Biology
 
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