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RSS FeedsCorrection: Mitosis-related phosphorylation of the eukaryotic translation suppressor 4E-BP1 and its interaction with eukaryotic translation initiation factor 4E (eIF4E). [Additions and Corrections] (Journal of Biological Chemistry)

 
 

4 april 2020 03:00:17

 
Correction: Mitosis-related phosphorylation of the eukaryotic translation suppressor 4E-BP1 and its interaction with eukaryotic translation initiation factor 4E (eIF4E). [Additions and Corrections] (Journal of Biological Chemistry)
 


VOLUME 294 (2019) PAGES 11840-11852In this study on mitotic mRNA translation, the authors report on cloned HeLa cell lines that were generated by CRISPR/Cas9 EIF4EBP1 knockout and then stable substitutions with either the EIF4EBP1 WT or codon S83A mutations. During cell line verification surveillance performed after publication, the authors found that 293T cells had been used instead of HeLa cells and were mislabeled (both HeLa and 293T cell lines had been initially targeted for EIF4EBP1 knockout). None of the conclusions are changed by this error. The authors regret the confusion generated by mis-stating the cell line used in this study and affirm the importance of routine cell line verification.


 
227 viewsCategory: Biochemistry
 
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