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RSS FeedsIJMS, Vol. 22, Pages 11267: Liquid Biopsies for Molecular Biology-Based Radiotherapy (International Journal of Molecular Sciences)

 
 

19 october 2021 12:07:12

 
IJMS, Vol. 22, Pages 11267: Liquid Biopsies for Molecular Biology-Based Radiotherapy (International Journal of Molecular Sciences)
 


Molecular alterations drive cancer initiation and evolution during development and in response to therapy. Radiotherapy is one of the most commonly employed cancer treatment modalities, but radiobiologic approaches for personalizing therapy based on tumor biology and individual risks remain to be defined. In recent years, analysis of circulating nucleic acids has emerged as a non-invasive approach to leverage tumor molecular abnormalities as biomarkers of prognosis and treatment response. Here, we evaluate the roles of circulating tumor DNA and related analyses as powerful tools for precision radiotherapy. We highlight emerging work advancing liquid biopsies beyond biomarker studies into translational research investigating tumor clonal evolution and acquired resistance.


 
57 viewsCategory: Biochemistry, Biophysics, Molecular Biology
 
IJMS, Vol. 22, Pages 11253: The Role of Mitochondria in Acute Kidney Injury and Chronic Kidney Disease and Its Therapeutic Potential (International Journal of Molecular Sciences)
IJMS, Vol. 22, Pages 11265: Toxic Effects of Indoxyl Sulfate on Osteoclastogenesis and Osteoblastogenesis (International Journal of Molecular Sciences)
 
 
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