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RSS FeedsIJMS, Vol. 22, Pages 11352: Receptor Tyrosine Kinases as Candidate Prognostic Biomarkers and Therapeutic Targets in Meningioma (International Journal of Molecular Sciences)

 
 

21 october 2021 10:09:52

 
IJMS, Vol. 22, Pages 11352: Receptor Tyrosine Kinases as Candidate Prognostic Biomarkers and Therapeutic Targets in Meningioma (International Journal of Molecular Sciences)
 


Meningioma (MGM) is the most common type of intracranial tumor in adults. The validation of novel prognostic biomarkers to better inform tumor stratification and clinical prognosis is urgently needed. Many molecular and cellular alterations have been described in MGM tumors over the past few years, providing a rational basis for the identification of biomarkers and therapeutic targets. The role of receptor tyrosine kinases (RTKs) as oncogenes, including those of the ErbB family of receptors, has been well established in several cancer types. Here, we review histological, molecular, and clinical evidence suggesting that RTKs, including the epidermal growth factor receptor (EGFR, ErbB1), as well as other members of the ErbB family, may be useful as biomarkers and therapeutic targets in MGM.


 
157 viewsCategory: Biochemistry, Biophysics, Molecular Biology
 
IJMS, Vol. 22, Pages 11353: Modification of Magnetite Nanoparticles with Triazine-Based Dendrons and Their Application as Drug-Transporting Systems (International Journal of Molecular Sciences)
IJMS, Vol. 22, Pages 11357: Auxin and Target of Rapamycin Spatiotemporally Regulate Root Organogenesis (International Journal of Molecular Sciences)
 
 
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