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RSS FeedsIJERPH, Vol. 18, Pages 12789: Passive Immunity to SARS-CoV-2 at Birth Induced by Vaccination in the First Trimester of Pregnancy (International Journal of Environmental Research and Public Health)

 
 

3 december 2021 21:58:55

 
IJERPH, Vol. 18, Pages 12789: Passive Immunity to SARS-CoV-2 at Birth Induced by Vaccination in the First Trimester of Pregnancy (International Journal of Environmental Research and Public Health)
 


As is well known, the COVID-19 infection is affecting the whole world, causing a serious health, social and economic crisis. The viral infection can cause a mild or severe illness, depending on how effectively the virus is countered by the immune system. In this context, the position of pregnant women remains rather unknown. The case described here reports the immune response in a woman in good health and in her newborn son, having undergone complete vaccination during the first trimester of her pregnancy. We performed a serological assay, measuring IgG antibodies to SARS-CoV-2, by a fully automated solid phase DELFIA (time-resolved fluorescence) immunoassay in a few drops of blood, collected by a finger-prick and spotted on filter paper. The dried blood spot (DBS) sample we used is the same type of sample routinely used in a newborn screening program test. Such a simple and minimally invasive approach allowed us to monitor both the mother and the newborn soon after birth for their anti-SARS-CoV-2 IgG levels. The serological test on the DBS carried out on both mother and newborn revealed the presence of anti-SARS-CoV-2 IgG antibodies up to 7 months after vaccination in the mother, and already at 48 h of life in the newborn.


 
38 viewsCategory: Medicine, Pathology, Toxicology
 
IJERPH, Vol. 18, Pages 12655: Influence of the Psychomotor Profile in the Improvement of Learning in Early Childhood Education (International Journal of Environmental Research and Public Health)
IJERPH, Vol. 18, Pages 12788: Earth Dreams: Reimagining ARPA for Health of People, Places, and Planet (International Journal of Environmental Research and Public Health)
 
 
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