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RSS FeedsIJERPH, Vol. 19, Pages 12257: Applying ACE-III, M-ACE and MMSE to Diagnostic Screening Assessment of Cognitive Functions within the Polish Population (International Journal of Environmental Research and Public Health)

 
 

27 september 2022 15:20:23

 
IJERPH, Vol. 19, Pages 12257: Applying ACE-III, M-ACE and MMSE to Diagnostic Screening Assessment of Cognitive Functions within the Polish Population (International Journal of Environmental Research and Public Health)
 


The research aims to compare the accuracy of the mini-mental state examination (MMSE), the Addenbrooke’s cognitive examination III (ACE-III) and the mini-Addenbrooke’s cognitive examination (M-ACE) within the Polish population. The model comprised several stages: the features of each test were compared; the shifts in result categorisations between the norm and below the norm were analysed; a third category—mild cognitive impairment (MCI)—was included. Additionally, particular ACE-III domains that scored below domain-specific norm thresholds were analysed to establish the potential early predictors of dementia. All tests correlated to a high and very high degree—cf. MMSE and ACE-III (r = 0.817; p < 0.001), MMSE and M-ACE (r = 0.753; p < 0.001), ACE-III and M-ACE (r = 0.942; p < 0.001). The area under the ROC curve for the ACE-III diagnostic variable had a high value (AUC = 0.920 ± 0.014). A cut-off point of 81 points was suggested for ACE-III; the M-ACE diagnostic variable had an equally high value (AUC = 0.891 ± 0.017). A cut-off point of 20 points was suggested. A significant decrease in the mean score values for people who scored norm or below the norm under ACE-III, as compared to the MMSE results for norm (p < 0.0001), occurred for speech fluency (which decreased by 26.4%). The tests in question are characterised by high sensitivity and specificity. Targeted ACE-III seems best recommended for use in specialised diagnostic centres, whereas M-ACE appears to be a better suited diagnostic alternative for primary health care centres in comparison to MMSE.


 
86 viewsCategory: Medicine, Pathology, Toxicology
 
IJERPH, Vol. 19, Pages 12281: ‘It’s All Downhill from Here’: A Scoping Review of Sports-Related Concussion (SRC) Protocols in Downhill Mountain Biking (DHI), with Recommendations for SRC Policy in Professional DMB (International Journal of Environmental Research and Public Health)
IJERPH, Vol. 19, Pages 12272: Predictive Model for Human Activity Recognition Based on Machine Learning and Feature Selection Techniques (International Journal of Environmental Research and Public Health)
 
 
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