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RSS FeedsIJMS, Vol. 23, Pages 11590: Prognostic and Immunological Role of STK38 across Cancers: Friend or Foe? (International Journal of Molecular Sciences)

 
 

30 september 2022 16:25:20

 
IJMS, Vol. 23, Pages 11590: Prognostic and Immunological Role of STK38 across Cancers: Friend or Foe? (International Journal of Molecular Sciences)
 


Although STK38 (serine-threonine kinase 38) has been proven to play an important role in cancer initiation and progression based on a series of cell and animal experiments, no systemic assessment of STK38 across human cancers is available. We firstly performed a pan-cancer analysis of STK38 in this study. The expression level of STK38 was significantly different between tumor and normal tissues in 15 types of cancers. Meanwhile, a prognosis analysis showed that a distinct relationship existed between STK38 expression and the clinical prognosis of cancer patients. Furthermore, the expression of STK38 was related to the infiltration of immune cells, such as NK cells, memory CD4+ T cells, mast cells and cancer-associated fibroblasts in a few cancers. There were three immune-associated signaling pathways involved in KEGG analysis of STK38. In general, STK38 shows a significant prognostic value in different cancers and is closely associated with cancer immunity.


 
56 viewsCategory: Biochemistry, Biophysics, Molecular Biology
 
IJMS, Vol. 23, Pages 11588: A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation (International Journal of Molecular Sciences)
IJMS, Vol. 23, Pages 11592: Nonthermal Plasma Effects on Fungi: Applications, Fungal Responses, and Future Perspectives (International Journal of Molecular Sciences)
 
 
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