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RSS FeedsIJMS, Vol. 23, Pages 11665: Saccharomyces cerevisiae as a Model System for Eukaryotic Cell Biology, from Cell Cycle Control to DNA Damage Response (International Journal of Molecular Sciences)

 
 

1 october 2022 14:24:06

 
IJMS, Vol. 23, Pages 11665: Saccharomyces cerevisiae as a Model System for Eukaryotic Cell Biology, from Cell Cycle Control to DNA Damage Response (International Journal of Molecular Sciences)
 


The yeast Saccharomyces cerevisiae has been used for bread making and beer brewing for thousands of years. In addition, its ease of manipulation, well-annotated genome, expansive molecular toolbox, and its strong conservation of basic eukaryotic biology also make it a prime model for eukaryotic cell biology and genetics. In this review, we discuss the characteristics that made yeast such an extensively used model organism and specifically focus on the DNA damage response pathway as a prime example of how research in S. cerevisiae helped elucidate a highly conserved biological process. In addition, we also highlight differences in the DNA damage response of S. cerevisiae and humans and discuss the challenges of using S. cerevisiae as a model system.


 
58 viewsCategory: Biochemistry, Biophysics, Molecular Biology
 
IJMS, Vol. 23, Pages 11664: Oxidative Stress and DNA Damage Markers in Colorectal Cancer (International Journal of Molecular Sciences)
IJMS, Vol. 23, Pages 11661: Characterization of the ABC Transporter G Subfamily in Pomegranate and Function Analysis of PgrABCG14 (International Journal of Molecular Sciences)
 
 
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