Molecules, Vol. 27, Pages 8275: Transformation of Amides to Thioamides Using an Efficient and Novel Thiating Reagent (Molecules)

A convenient protocol was developed for the transformation of N-aryl-substituted benzamides to N-aryl-substituted benzothioamides using N-isopropyldithiocarbamate isopropyl ammonium salt as a novel thiating reagent. The major advantages of this protocol are its one-pot procedure, short reaction times, mild conditions, simple work-up, high yields and pure products.