MyJournals Home  

RSS FeedsComparison of exercise electrocardiography and stress perfusion CMR for the detection of coronary artery disease in women (Journal of Cardiovascular Magnetic Resonance)


14 june 2012 16:32:45

Comparison of exercise electrocardiography and stress perfusion CMR for the detection of coronary artery disease in women (Journal of Cardiovascular Magnetic Resonance)

Background: Exercise electrocardiography (ECG) is frequently used in the work-up of patients withsuspected coronary artery disease (CAD), however the accuracy is reduced in women.Cardiovascular magnetic resonance (CMR) stress testing can accurately diagnose CAD inwomen. To date, a direct comparison of CMR to ECG has not been performed.Methods and resultsWe prospectively enrolled 88 consecutive women with chest pain or other symptomssuggestive of CAD. Patients underwent a comprehensive clinical evaluation, exercise ECG, aCMR stress test including perfusion and infarct imaging, and x-ray coronary angiography(CA) within 24 hours. CAD was defined as stenosis [greater than or equal to]70% on quantitative analysis of CA.Exercise ECG, CMR and CA was completed in 68 females (age 66.4 +/- 8.8 years, number ofCAD risk factors 3.5 +/- 1.4). The prevalence of CAD on CA was 29%. The Duke treadmillscore (DTS) in the entire group was 3.0 +/- 5.4 and was similar in those with and withoutCAD (4.5 +/- 5.8 and 2.4 +/- 5.1; P = 0.12). Sensitivity, specificity and accuracy for CADdiagnosis was higher for CMR compared with exercise ECG (sensitivities 85% and 50%,P = 0.02, specificities 94% and 73%, P = 0.01, and accuracies 91% and 66%, P = 0.0007,respectively). Even after applying the DTS the accuracy of CMR was higher compared toexercise ECG (area under ROC curve 0.94 +/- 0.03 vs 0.56 +/- 0.07; P = 0.0001). Conclusions: In women with intermediate-to-high risk for CAD who are able to exercise and haveinterpretable resting ECG, CMR stress perfusion imaging has higher accuracy for thedetection of relevant obstruction of the epicardial coronaries when directly compared toexercise ECG. Digg Facebook Google StumbleUpon Twitter
137 viewsCategory: Biophysics, Cardiology
Perfusion cardiovascular magnetic resonance: Comparison of an advanced, high-resolution and a standard sequence (Journal of Cardiovascular Magnetic Resonance)
In vivo chronic myocardial infarction characterization by spin locked cardiovascular magnetic resonance (Journal of Cardiovascular Magnetic Resonance)

The articles that are most similar to this article

No articles have been found that are similar to this article.
blog comments powered by Disqus
The latest issues of all your favorite science journals on one page


Register | Retrieve



Use these buttons to bookmark us: Digg Facebook Google StumbleUpon Twitter

Valid HTML 4.01 Transitional
Copyright © 2008 - 2016 Indigonet Services B.V.. Contact: Tim Hulsen
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Travel Photos Nachrichten Indigonet Finances Leer Mandarijn
Indigonet Services BV is not responsible for any incorrect or outdated information on this site.
If, however, you would like to see an article removed, you can send us an e-mail quoting the article number.