Connective tissue diseases: Adipocyte-myofibroblast transition: linking intradermal fat loss to skin fibrosis in SSc (Nature Clinical Practice Rheumatology)

Myofibroblasts are considered the primary fibrogenic effector cells in systemic sclerosis (SSc), but the origin of these cells within fibrotic lesions is a matter of debate. A new study published in Arthritis & Rheumatology shows that the majority of dermal myofibroblasts in fibrotic skin