The effect of short-term high versus normal protein intake on whole-body protein synthesis and balance in children following cardiac surgery: a randomized double-blind controlled clinical trial (Nutrition Journal)

Background: Infants undergoing cardiac surgery are at risk of a negative protein balance, due to increased proteolysis in response to surgery and the cardiopulmonary bypass circuit, and limited intake. The aim of the study was to quantify the effect on protein kinetics of a short-term high-protein (HP) diet in infants following cardiac surgery. Methods: In a prospective, double-blinded, randomized trial we compared the effects of a HP (5 g · kg −1  · d −1 ) versus normal protein (NP, 2 g · kg −1  · d −1 ) enteral diet on protein kinetics in children