MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production (Immunity)

MicroRNAs (miRNAs) are important regulators of cell fate decisions in immune responses. Ansel and colleagues identify miR-24 and miR-27 as inhibitors of Th2 cell differentiation and function and use miRNA-directed pathway discovery to elucidate a gene network upstream of interleukin-4 production in T cells.