Mass Cytometry of the Human Mucosal Immune System Identifies Tissue- and Disease-Associated Immune Subsets (Immunity)

The role of immune subsets in intestinal pathology has been studied, but a system-wide analysis is lacking. Koning and colleagues use mass cytometry to dissect the human mucosal immune system in health and disease. They identify immune subsets with tissue- and disease-specificity with implications for diagnostic procedures and individualized therapeutics.