Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis (Current Biology)

The composition and function of the central core region of centrioles is ill defined. Using mass spectrometry and super-resolution microscopy, Hamel et al. discover POB15 and POC16 as two Chlamydomonas central core components. They further establish that POC16 and its human homolog WDR90 are required for efficient flagella/cilia formation.