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RSS FeedsVirus-Mediated Genome Editing via Homology-Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain (Neuron)

 
 

19 october 2017 19:46:27

 
Virus-Mediated Genome Editing via Homology-Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain (Neuron)
 


Nishiyama et al. show that precise genome editing via HDR is possible in mature postmitotic neurons as well as mitotic cells in the mammalian brain by combining CRISPR-Cas9-mediated DNA cleavage and the efficient delivery of donor template with AAV.


 
127 viewsCategory: Neurology
 
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