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RSS FeedsGDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death (Cell Chemical Biology)

 
 

18 december 2017 23:46:33

 
GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death (Cell Chemical Biology)
 


Sieber et al. implement a high-throughput screening assay of podocyte viability and find that the BRAF inhibitor GDC-0879 protects podocytes by restoring MAPK signaling, offering a novel repurposing strategy for targeted kidney therapeutics.


 
135 viewsCategory: Biology, Chemistry, Biochemistry
 
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