Marine Drugs, Vol. 15, Pages 392: New Cytotoxic Terpenoids from Soft Corals Nephthea chabroli and Paralemnalia thyrsoides (Marine Drugs)

A novel cytotoxic diterpenoid, chabrolin A (1) (possessing an unprecedented terpenoid skeleton), as well as three new cytotoxic sesquiterpenoids, parathyrsoidins E-G (2-4), were isolated by cytotoxicity-guided fractionation from soft corals Nephthea chabroli and Paralemnalia thyrsoides. The structures of the new compounds were determined by extensive analysis of spectroscopic data.