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RSS FeedsGenomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer (Cancer Cell)

 
 

14 april 2018 06:00:21

 
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer (Cancer Cell)
 




Hellmann et al. examine non-small-cell lung cancers treated with combined PD-1 and CTLA-4 blockade using whole-exome sequencing and find that high tumor mutation burden is the strongest feature associated with improved objective response, durable benefit, and progression-free survival in multivariable analysis.


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88 viewsCategory: Cell Biology, Oncology
 
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Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia (Cancer Cell)
 
 
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