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RSS FeedsFlaviviruses Exploit the Lipid Droplet Protein AUP1 to Trigger Lipophagy and Drive Virus Production (Cell Host & Microbe)

 
 

18 june 2018 12:02:00

 
Flaviviruses Exploit the Lipid Droplet Protein AUP1 to Trigger Lipophagy and Drive Virus Production (Cell Host & Microbe)
 


Zhang et al. describe the role of AUP1, a lipid droplet-associated host factor that is exploited during flavivirus infections. Viral non-structural proteins NS4A and NS4B interact with AUP1 to hijack its acyltransferase function, triggering the consumption of lipid droplets to facilitate production of progeny virus particles.


 
107 viewsCategory: Cell Biology, Immunology, Microbiology
 
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