Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease (Cell Host & Microbe)

Many metabolites are involved in host-microbiota interactions. Agus et al. review recent advances concerning the central role of tryptophan metabolism in microbiota-host crosstalk in health and disease. This review examines the direct effect of the gut microbiota in producing tryptophan-derived bioactive molecules and its indirect control of host tryptophan metabolism.