Microtubule End-Clustering Maintains a Steady-State Spindle Shape (Current Biology)

Hueschen et al. show that mitotic spindles use clustering of microtubule ends by the motor dynein to maintain a steady-state spindle network shape. After complete loss of dynein or its partner NuMA, spindles dynamically remodel their shape and microtubule organization, and these unstable turbulent spindles can drive cell movement.